Biomarkers predict conversion from clinically isolated syndrome to multiple sclerosis
نویسندگان
چکیده
منابع مشابه
Protein-Based Classifier to Predict Conversion from Clinically Isolated Syndrome to Multiple Sclerosis.
Multiple sclerosis is an inflammatory, demyelinating, and neurodegenerative disease of the central nervous system. In most patients, the disease initiates with an episode of neurological disturbance referred to as clinically isolated syndrome, but not all patients with this syndrome develop multiple sclerosis over time, and currently, there is no clinical test that can conclusively establish wh...
متن کاملconversion from radiologically isolated syndrome to multiple sclerosis
background: the aim of this study was to estimate the conversion rate from radiologically isolated syndrome (ris) to definite multiple sclerosis (ms). methods: during a mean (standard deviation [sd]) follow-up period of 17.4 (5.4) (range 8-29) months, 25 subjects with ris and without neurological symptom aged 22-45 year from a single-center have been examined for the occurrence of definite ms. ...
متن کاملPredictors and Conversion Rate of Clinically Isolated Syndrome to Clinically Definite Multiple Sclerosis: A Follow-up Study in Patients Living in the Southern Part of Iran
Background: Clinical course of Clinically Isolated Syndrome (CIS) is variable, and identifying patients who will eventually develop Multiple Sclerosis (MS) is essential. Objectives: To assess the conversion rate of CIS to Clinically Definite Multiple Sclerosis (CDMS) and its predictors in southern Iran. Materials & Methods: A total of 143 CIS patients registered to Fars Multiple Sclerosis Soc...
متن کاملConversion from Radiologically Isolated Syndrome to Multiple Sclerosis
BACKGROUND The aim of this study was to estimate the conversion rate from radiologically isolated syndrome (RIS) to definite multiple sclerosis (MS). METHODS During a mean (standard deviation [SD]) follow-up period of 17.4 (5.4) (range 8-29) months, 25 subjects with RIS and without neurological symptom aged 22-45 year from a single-center have been examined for the occurrence of definite MS. ...
متن کاملIgG Antibodies against Measles, Rubella, and Varicella Zoster Virus Predict Conversion to Multiple Sclerosis in Clinically Isolated Syndrome
BACKGROUND Multiple sclerosis (MS) is characterized by a polyspecific B-cell response to neurotropic viruses such as measles, rubella and varicella zoster, with the corresponding antibodies measurable in CSF as the so-called "MRZ reaction" (MRZR). We aimed to evaluate the relevance of MRZR to predict conversion of patients with clinically isolated syndrome (CIS) to MS, and to compare it to olig...
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ژورنال
عنوان ژورنال: Nature Reviews Neurology
سال: 2015
ISSN: 1759-4758,1759-4766
DOI: 10.1038/nrneurol.2015.32